Chemical constituents of Peperomia tetraphylla (Forst. F.) Hooker et Arnott |
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| Affiliation: | 1. College of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, 250355, Shandong Province, PR China;2. China Tobacco Henan Industrial Co. Ltd, Zhengzhou, 450000, PR China;1. Laboratory of Environmental and Applied Chemistry, Department of Chemistry, Faculty of Science, University of Dschang, Box 183, Dschang, Cameroon;2. School of Science and Technology, Chemistry Division, University of Camerino, Via S. Agostino 1, I-62032 Camerino, Italy;3. Laboratoire de Pharmacognosie, UFR des Sciences de Santé (Pharmacie), EA 4267 (FDE/UFC), Université de Bourgogne, 7, Boulevard Jeanne d’Arc, BP 87900, 21079 Dijon Cedex, France;4. School of Pharmacy, Physiology Division, University of Camerino, Via Gentile III da Varano, I-62032 Camerino, Italy;1. School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, 110016, PR China;2. Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang, 110032, PR China;1. School of Pharmacy, Jiangxi University of Chinese Medicine, Nanchang, 330004, People′s Republic of China;2. State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, People′s Republic of China;1. School of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, 712046, China;2. Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, BeiJing, 100700, China;3. Shaanxi Institute of International Trade & Commerce, Xianyang, 712046, China;1. National Engineering Research Center of Navel Orange, Gannan Normal University, Ganzhou, 341000, PR China;2. Key Laboratory of Plant Resources Conservation and Sustainable Utilization, South China Botanical Garden, Chinese Academy of Science, Guangzhou, 510650, PR China;1. Department of Organic Chemistry, Faculty of Science, The University of Yaoundé 1, P.O. Box 812, Yaoundé, Cameroon;2. Drug Discovery and Smart Molecules Research Laboratory, Department of Chemical Sciences, University of Johannesburg, P.O. Box 1711, Doornfontein, Johannesburg, 2028, South Africa;3. Center for Natural Product Research (CNPR), Chemical Sciences Department, University of Johannesburg, 2028, South Africa;4. Research Center for Synthesis and Catalysis; Department of Chemical Sciences, University of Johannesburg-Kingsway Campus, Auckland Park, 2008, South Africa;5. Laboratory of Phytobiochemistry and Medicinal Plants Studies, Faculty of Science, The University of Yaoundé 1, P.O. Box 812, Yaoundé, Cameroon;6. Laboratory of Pharmacology, Centre for Research on Medicinal Plants and Traditional Medicine, Institute of Medical Research and Medicinal Plants Studies, P.O. Box 13033, Yaoundé, Cameroon;7. Laboratoire de chimie des Substances naturelles, Muséum National d’Histoire Naturelle, 63 Rue Buffon, 75005, Paris, France |
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| Abstract: | Sixteen compounds were isolated from the whole herbs of Peperomia tetraphylla (Forst. F.) Hooker et Arnott by phytochemical methods, including eight flavonoids (1–3, 6, 7, 14–16), three lignans (8–10), three beta sitosterols (4, 5, 11), and two phenolic acids (12, 13). Their structures were identified by the analysis of NMR and MS, as well as the comparisons to the reported data. Among them, 2″-O-xylosylisoswertisin (14) was firstly isolated from the Piperaceae family, as well as ten compounds (1–4, 7, 10–11, 13, 15–16) were isolated from P. tytraphylla for the first time. Moreover, the chemotaxonomic significance of constituents isolated from P. tytraphylla was also discussed. |
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| Keywords: | Chemical constituents Chemotaxonomic significance |
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