Abstract: | A mathematical model for studies of peculiar features of the dynamics of local conformational distortions (kinks) has been constructed. General formulas determining the dependence of the main dynamic characteristics of kinks: size, energy, density of energy, and velocity on the composition of inhomogeneous DNA have been obtained. Quantitative estimations of the characteristics have been made for kinks activated in inhomogeneous polynucleotide chains with sequences analogous to promoter sequences A1, A2, and A3 of bacteriophage T7 genome. |