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Mapping of virginiamycin S resistance in Bacillus subtilis
Authors:E Z Ron  M P de Bethune  C G Cocito
Affiliation:(1) Department of Microbiology, Tel Aviv University, Tel Aviv, Israel;(2) Department of Microbiology and Genetics, Institute of Cell Pathology, University of Louvain, 1200 Brussels, Belgium
Abstract:Summary Resistance to virginiamycin S (VS, a type B synergimycin) has been mapped in Bacillus subtilis. Transduction experiments with phage PBS1 indicate that the gene for virginiamycin S resistance (VSR) is cotransduced with the markers pur A16 (20%) and cys A14 (46–49%). Transformation experiments indicate that the gene for virginiamycin S resistance maps between the markers for elongation factor G and erythromycin resistance, and is therefore located within the gene cluster of ribosomal proteins.
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