A ferroxidase encoded by FOX1 contributes to iron assimilation under conditions of poor iron nutrition in Chlamydomonas |
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Authors: | Chen Jen-Chih Hsieh Scott I Kropat Janette Merchant Sabeeha S |
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Institution: | Department of Chemistry and Biochemistry, Box 951569, University of California—Los Angeles, Los Angeles, California 90095-1569 |
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Abstract: | When the abundance of the FOX1 gene product is reduced, Chlamydomonas cells grow poorly in iron-deficient medium, but not in iron-replete medium, suggesting that FOX1-dependent iron uptake is a high-affinity pathway. Alternative pathways for iron assimilation, such as those involving ZIP family transporters IRT1 and IRT2, may be operational. |
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