Scoring approach based on fish biomarkers applied to French river monitoring |
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Authors: | Nadia Aarab Olivier Champeau Pascal Mora Mich le Daubeze Philippe Garrigues Jean-Fran ois Narbonne |
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Affiliation: | Laboratoire de Physico-Toxicochimie des systèmes Naturels, UMR 5472 CNRS, Université Bordeaux I, F-33405 Talence, France. |
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Abstract: | The aim was to apply a multimarker scoring approach as complementary to freshwater monitoring programmes carried out by the Water Agency Adour-Garonne. Fish (chub, barbel and trout) were collected in 11 sites in rivers in south-west France. Five biomarkers of response were measured either in muscle or brain for acetylcholinesterase (AChE) and in liver for glutathione S-transferase, catalase and 7-ethoxyresorufine O-deethylase. As a result of multivariate analysis, sites were clearly discriminated mainly by 7-ethoxyresorufine O-deethylase and acetylcholinesterase activities. According to the scoring approach, a multimarker pollution index was calculated for each sampling site as the sum of the response index of the five measured biomarkers (pollution index). Sorting was established by ranging the sites from lightly to highly contaminated locations. |
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Keywords: | exposure biomarkers fish freshwater scoring approach pollution index |
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