Microbial production and applications of chiral hydroxyalkanoates |
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| Authors: | Guo-Qiang Chen Qiong Wu |
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| Affiliation: | (1) MOE Laboratory of Protein Science, Department of Biological Sciences and Biotechnology, Tsinghua University, Beijng, 100084, China;(2) Multidisciplinary Research Center, Shantou University, Shantou, Guangdong, 515063, China |
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| Abstract: | Polyhydroxyalkanoates (PHA) are a family of polyesters consisting of over 150 chiral hydroxyalkanoic acids (HA). This paper reviews the physiological functions of (R)-3-hydroxybutyric acid (3HB) and (R)-4-hydroxybutyric acid and summarizes the technologies developed to produce various HA [3HB, (R)-3-hydroxyoctanoic acid, (R)-3-hydroxydecanoic acid, etc.] and the applications of chiral HA. Their outlooks and perspectives are discussed. |
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