Radical-scavenging activities of new hydroxylated ursane triterpenes from cv. Annurca apples |
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Authors: | D'Abrosca Brigida Fiorentino Antonio Monaco Pietro Pacifico Severina |
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Institution: | Dipartimento di Scienze della Vita, Seconda Università degli Studi di Napoli, via Vivaldi 43, I-81100 Caserta. |
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Abstract: | Two new ursolic acid triterpene derivatives, compounds 2 and 3, have been isolated from cv. Annurca apple fruit, a high-quality apple variety widely cultivated in southern Italy, together with the known 2-oxopomolic acid (1). The new compounds were identified by means of different spectroscopic techniques as 3-epi-2-oxopomolic acid (= (3alpha)-3,19-dihydroxy-2-oxours-12-en-28-oic acid; 2) and (1alpha)-1-hydroxy-3-oxours-12-en-28-oic acid (3). Compounds 1-3 were tested for their radical-scavenging activities with the aid of a 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay (Fig. 2). All three constituents showed activities similar to that of the reference antioxidant alpha-tocopherol (vitamin E). |
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