Na+-glucose cotransporter (SGLT) inhibitory flavonoids from the roots of Sophora flavescens |
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| Authors: | Sato Seizo Takeo Jiro Aoyama Chihiro Kawahara Hiroyuki |
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| Affiliation: | Central Research Laboratory, Nippon Suisan Kaisha, Ltd, 559-6 Kitano-machi, Hachioji, Tokyo 192-0906, Japan. s-satou@nissui.co.jp |
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| Abstract: | The methanol extract of Sophora flavescens, which is used in traditional Chinese medicine (sophorae radix), showed potent Na(+)-glucose cotransporter (SGLT) inhibitory activity. Our search for active components identified many well-known flavonoid antioxidants: kurarinone, sophoraflavanone G, kushenol K, and kushenol N. |
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