Patient-specific tumor and respiratory monitoring phantom design for quality controls of stereotactic ablative body radiotherapy in lung cancer cases |
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| Affiliation: | 1. Department of Radiation Oncology, Afyonkarahisar Health Sciences University Faculty of Medicine, 03030 Afyonkarahisar, Turkey;2. Department of Biomedical Engineering, Afyonkocatepe University Faculty of Engineering, 03030 Afyonkarahisar, Turkey;3. Department of Radiation Oncology, Cancer Institute, Hacettepe University Faculty of Medicine, 06100 Ankara, Turkey;1. AOU Careggi, Medical Physics Unit, Florence, Italy;2. University of Florence-Department of Experimental and Clinical Biomedical Sciences “Mario Serio”, Florence, Italy;3. AOU Careggi, Radiotherapy Unit, Florence, Italy;4. Santa Maria Annunziata Hospital, Radiation Oncology Unit, Florence, Italy;1. Section of Radiotherapy Physics and Engineering, Department of Medical Radiation Physics and Nuclear Medicine, Karolinska University Hospital, Stockholm, Sweden;2. Department of Oncology and Pathology, Karolinska Institutet, Stockholm, Sweden;3. Section of Thoracic Radiology, Department of Radiology, Karolinska University Hospital, Stockholm, Sweden;4. Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden;5. Section of Head, Neck, Lung and Skin Tumours, Department of Cancer, Karolinska University Hospital, Stockholm, Sweden;6. Section of Radiotherapy, Department of Cancer, Karolinska University Hospital, Stockholm, Sweden;7. Department of Medical Radiation Physics and Nuclear Medicine, Karolinska University Hospital, Stockholm, Sweden;1. Dept. of Clinical Physics and Bio-Engineering, University of Glasgow, Gartnavel Royal Hospital, Glasgow G12 0XH, UK;2. Dept. of Physical Sciences, Peter MacCallum Cancer Centre, 305 Grattan Street, Melbourne, VIC 3000, Australia;3. International Atomic Energy Agency, Vienna International Centre, PO Box 100, 1400 Vienna, Austria;4. Medical Physics Service, Queen’s Centre, Castle Hill Hospital, Hull University Teaching Hospitals NHS Trust, Castle Road, Hull HU16 5JQ, UK;5. Faculty of Science and Engineering, University of Hull, Cottingham Road, Hull HU6 7RX, UK;6. Dept. of Health Informatics and Data Science, Parkinson School of Health Sciences and Public Health, Loyola University, Chicago, IL, USA;7. Clinical Oncology Unit, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia;8. Loyola University Chicago, Stritch School of Medicine, Department of Radiation Oncology, Cardinal Bernardin Cancer Center, Maywood, IL 60153 USA;9. Dept. of Medical Physics, German Oncology Center, Limassol 4108, Cyprus;10. Physics Dept., Sciences Faculty, Universidad Nacional de Colombia, Bogotá, Colombia;11. Cancer Institut “Carlos Ardila Lülle”, Santa Fe Foundation, Bogota, Colombia;12. Faculty of Nature and Life Sciences, University of El-Oued, PO Box 789, El-Oued, Algeria;13. Dept. of Medical Technology and Physics, Sir Charles Gairdner Hospital, Hospital Avenue, Nedlands, WA 6009, Australia;14. Baheya Center for Early Detection & Breast Cancer Treatment, 4 Aloba St. of Haram St. Dari Center, Giza, Egypt;15. The National Center for Applied Physics, King Abdulaziz City for Science and Technology (KACST), P.O. Box: 6086, Riyadh, Saudi Arabia;p. Task Group 116 member, International Commission on Radiological Protection, 280 Slater Street, Ottawa, Ontario K1P 5S9, Canada;q. Mentorship programme, International Commission on Radiological Protection, 280 Slater Street, Ottawa, Ontario K1P 5S9, Canada;1. Department of Radiation Oncology, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, NO. 651 Dongfeng Road, Guangzhou 510060, China;2. Department of Radiotherapy, Zhongshan Affiliated Hospital, Guangzhou University of Chinese Medicine, NO. 3 Kangxin Road West District, Zhongshan 528401, China;1. Department of Radiation Oncology, Fujian Medical University Union Hospital, Fuzhou, China;2. Fujian Medical University Union Clinical Medicine College, Fujian Medical University, Fuzhou, China;3. Department of Medical Imaging Technology, College of Medical Technology and Engineering, Fujian Medical University, Fuzhou, China |
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| Abstract: | The design, production and adaptability to clinical routine of a patient-specific tumor and respiratory monitoring phantom (TRMP) was investigated using 3D printer technology. TRMP and GTV modelling were done using 4D-CT images of the inhalation phase. The model was converted to STL (Stereolithography) format and printed with STH (Strong Herbal) biopolymer with HU (Hounsfield Unit) suitable for imaging purposes. The assembly of TRMP motorized parts and mechanical equipment has been completed and made suitable for clinical use. In the first part of the study, the deviations of radio-opaque markers attached to the TRMP sternum to perform mechanical quality control tests and T1-7 costal vertebrae in CC, AP, and LAT directions were evaluated. In the second part of the study, in order to evaluate the usability of the TRMP in quality assurance (QA), point dose measurements with BeO OSL dosimetry and EBT3 gafchromic film measurements were taken in Trilogy® radiotherapy accelerator and CyberKnife® robotic radiosurgery accelerator. In this study, we present a highly flexible TMRP capable of performing independent internal and external motions. TRMP was successfully tested in different treatment accelerators, both mechanically and dosimetrically. |
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| Keywords: | 3D Dynamic Phantom Lung SABR OSL |
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