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Production of polyhydroxyalkanoates (PHAs) from waste materials and by-products by submerged and solid-state fermentation
Authors:Leda R Castilho  David A Mitchell  Denise MG Freire
Institution:aFederal University of Rio de Janeiro (UFRJ), COPPE, Chemical Engineering Program, Caixa Postal 68502, 21941-972 Rio de Janeiro/RJ, Brazil;bFederal University of Paraná (UFPR), Department of Biochemistry, Caixa Postal 19046, Jardim das Américas, 81531-990 Curitiba/PR, Brazil;cFederal University of Rio de Janeiro (UFRJ), IQ, Department of Biochemistry, CT, Bl. A, Lab. 549-2, 21949-900 Rio de Janeiro/RJ, Brazil
Abstract:Polyhydroxyalkanoates are biodegradable polymers produced by prokaryotic organisms from renewable resources. The production of PHAs by submerged fermentation processes has been intensively studied over the last 30 years. In recent years, alternative strategies have been proposed, such as the use of solid-state fermentation or the production of PHAs in transgenic plants. This paper gives an overview of submerged and solid-state fermentation processes used to produce PHAs from waste materials and by-products. The use of these low-cost raw materials has the potential to reduce PHA production costs, because the raw material costs contribute a significant part of production costs in traditional PHA production processes.
Keywords:Biodegradable polymers  Bacterial polyesters  Polyhydroxyalkanoates (PHAs)  Submerged fermentation  Solid-state fermentation
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