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Evidence against Na+-pump mediation of Ca2+-activated K+ transport and diuretic-sensitive (Na+/K+)-cotransport
Authors:SJD Karlish  JC Ellory  VL Lew
Institution:1. Biochemistry Department, Weizmann Institute, Rehovoth Israel;2. Physiological Laboratory, University of Cambridge, Downing Street, Cambridge, CB2 3EG U.K.
Abstract:Proteoliposomes reconstituted from purified Na+ pumps show neither Ca2+ activation nor bumetanide inhibition of Rb+ uptake, suggesting that the Na+ pump does not mediate these passive fluxes.
Keywords:Diuretic sensitivity
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