Announcement - Reference List |
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| Authors: | L Beaugè R DiPolo L Osses F Barnola M Campos |
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| Institution: | 1. Division de Biofisica, Instituto de Investigacion Medica M. y M. Ferreyra, Castilla de Correo 389, 5000 Cordoba Argentina;2. Centro de Biofisica y Bioquimica, Instituto Venezolano de Investigaciones Cientificas, Apartado 1827, Caracas Venezuela |
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| Abstract: | A (Ca2+, Mg2+)-ATPase activity and a (Ca2+, Mg2+)-dependent phosphorylation from ATP have been found in plasma membrane fragments from squid optical nerves under conditions where contamination by intracellular organelles is unlikely. The properties of this (Ca2+, Mg2+)-ATPase activity are almost identical to those of the ATP-dependent uncoupled Ca2+ efflux observed in dialyzed squid giant axons. This gives further support to the notion that the mechanism responsible for maintaining the low levels of ionized Ca concentration in nerves at rest is not a Na+-Ca2+ exchange system but an ATP-driven uncoupled Ca2+ pump. |
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| Keywords: | Squid optical axons |
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