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Influence of stearic acid monolayers upon the procaine adsorption from underlying alkaline aqueous solutions
Institution:1. Technical University of Cluj-Napoca, 28 Memorandumului Street, 400114, Cluj-Napoca, Romania;1. UR1268 Biopolymères Interactions Assemblages, Institut National de la Recherche Agronomique, rue de la Géraudière, F-44316 Nantes cedex 3, France;2. Institut de Physique de Rennes, UMR CNRS 6251, Université Rennes 1, Rennes, France;1. National Institute for Research and Development of Isotopic and Molecular Technologies, Department of Molecular and Biomolecular Physics, 67-103 Donat Street, Cluj-Napoca 400293, Romania;2. Faculty of Chemistry and Chemical Engineering, Department of Chemical Engineering, Research Center of Physical Chemistry, Babe?-Bolyai University, 11 Arany Janos Street, Cluj-Napoca 400028, Romania;3. Academy of Romanian Scientists, 54 Splaiul Independentei, Bucharest 050085, Romania;1. Technical University of Cluj-Napoca, 28 Memorandumului Street, 400000 Cluj-Napoca, Romania;2. “Iuliu Ha?ieganu” University of Medicine and Pharmacy, 8 Victor Babes Street, 400012 Cluj-Napoca, Romania;3. University of Agricultural Science and Veterinary Medicine, 3-5 Calea Manastur Street, 400372 Cluj-Napoca, Romania;4. Regional Institute of Gastroenterology and Hepatology \"Prof. Dr. O. Fodor\", 19-21 Croitorilor Street, 400162 Cluj-Napoca, Romania;5. National Institute for Research and Development of Isotopic and Molecular Technologies, 67-103 Donath Street, 400293 Cluj-Napoca, Romania;6. Babes-Bolyai University, 5-7 Clinicilor Street, 400084 Cluj-Napoca, Romania;7. MedFuture Research Center for Advanced Medicine, “Iuliu Ha?ieganu” University of Medicine and Pharmacy Cluj-Napoca, 4 Louis Pasteur Street, 400349 Cluj-Napoca, Romania
Abstract:Adsorption of procaine at the air/water interface and its penetration into stearic acid monolayers from aqueous subphase of pH 8 are studied by measuring surface tension of aqueous procaine solutions and by recording surface pressure vs. mean molecular area curves for stearic acid monolayers spread onto procaine solutions of different concentrations. The amount of procaine in the interface is derived by means of Gibbs' equation. Results are compared to those obtained earlier at pH 2 and on unbuffered subphases. With increasing pH an increasing procaine adsorption and procaine penetration is observed. This phenomenon is interpreted in terms of protolytic equilibria in which participate both surfactants procaine and stearic acid.
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