A human RNA polymerase II subunit is encoded by a recently generated multigene family |
| |
| Authors: | Sylvie Grandemange Sophie Schaller Shigeru Yamano Stanislas Du Manoir George V Shpakovski Marie-Geneviève Mattei Claude Kedinger Marc Vigneron |
| |
| Institution: | (1) Department of Cancer Genetics, Roswell Park Cancer Institute, Buffalo, NY, USA;(2) Division of Developmental Biology, Children's Hospital Research Foundation, Cincinnati, OH, USA |
| |
| Abstract: | Background Some origins in eukaryotic chromosomes fire more frequently than others. In the fission yeast, Schizosaccharomyces pombe, the relative firing frequencies of the three origins clustered 4-8 kbp upstream of the ura4 gene are controlled by a replication enhancer - an element that stimulates nearby origins in a relatively position-and orientation-independent fashion. The important sequence motifs within this enhancer were not previously localized. |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
|
