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Effect of irradiation on the cellular sensitivity of separate NKLy tumor subpopulations to the membrane-toxic action of natural killers
Authors:G G Slivinski?  O I Krifuks  I N Magda
Abstract:A study was made of sensitivity of NKLy tumor fractions, differing in the proliferative activity, position in the cell cycle, and ploidy, to membrane-toxic action of natural killer cells from mouse spleen. The membrane toxicity index for cells of three out of five fractions under study was shown to decrease after exposure to 4 Gy radiation. It is concluded that there is no correlation between NKLy cell sensitivity to membrane-toxic effect of natural killer cells and their radiosensitivity as well as their ability to repair potentially lethal damages.
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