Genes encoding novel secreted and transmembrane proteins are temporally and spatially regulated during Drosophila melanogaster embryogenesis |
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| Authors: | Alejandro Zú?iga Christian H?dar Patricia Hanna Freddy Ibá?ez Pablo Moreno Rodrigo Pulgar Luis Pastenes Mauricio González and Verónica Cambiazo |
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| Institution: | (1) Laboratorio de Bioinform?tica y Expresi?n G?nica, Millennium Nucleus Center for Genomics of the Cell (CGC), INTA-Universidad de Chile, Santiago, Chile |
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| Abstract: | Background Morphogenetic events that shape the Drosophila melanogaster embryo are tightly controlled by a genetic program in which specific sets of genes are up-regulated. We used a suppressive
subtractive hybridization procedure to identify a group of developmentally regulated genes during early stages of D. melanogaster embryogenesis. We studied the spatiotemporal activity of these genes in five different intervals covering 12 stages of embryogenesis. |
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