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Improved glucoamylase production by less unstable strains ofAspergillus awamori
Authors:Airton Vialta  Renato Bonatelli Junior
Affiliation:(1) Codetec, P.O. Box 6041, 13081 Campinas, S.P., Brasil;(2) Dept. of Genetics and Evolution, IB-UNICAMP, P.O.Box 6109, 13081 Campinas, S.P., Brasil
Abstract:Summary The NRRL 3112 strain ofAspergillus awamori showed spontaneous segregation and sector formation tentatively attributed to a chromosomal instability. Spontaneous segregants showing stablepro1 (proline) requirement were easily isolated and stablepro+ strains were not isolated at all. Derivatives showing lower frequency ofpro1 conidia produced significantly more glucoamylase than the parental strain.
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