Population consequences of mutational events: effects of antibiotic resistance on the <Emphasis Type="Italic">r</Emphasis>/<Emphasis Type="Italic">K</Emphasis> trade-off |
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Authors: | Jay M Fitzsimmons Sijmen E Schoustra Jeremy T Kerr Rees Kassen |
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Institution: | (1) Department of Biology, University of Ottawa, 30 Marie Curie, Ottawa, ON, K1N 6N5, Canada;(2) Department of Biology and Centre for Advanced Research in Environmental Genomics, University of Ottawa, 30 Marie Curie, Ottawa, ON, K1N 6N5, Canada |
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Abstract: | What are the effects of a mutational event on population dynamics? This eco-evolutionary question has relevance not only to basic biological theories but also to conservation applications. We evaluated the relationship between maximum population growth rate (r max) and carrying capacity (K) among strains of the bacterium Pseudomonas fluorescens. Each of 65 strains differed from their common ancestor by one naturally acquired phenotypic change conferring antibiotic resistance, brought about by a single mutational event, and each was grown in isolation in four environments. We found no evidence of a trade-off between r max and K. Rather, strains with rapid growth rates also had high carrying capacity, with little interaction between strain and environment. We conclude that the extensive variation in overall fitness resulting from single mutational events likely masks whatever population trade-offs may exist. |
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