Dimorphism-associated changes in amino acid transport of Candida albicans |
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Authors: | Simminder Kaur Prashant Mishra Rajendra Prasad |
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Affiliation: | Membrane Biology Unit, School of Life Sciences, Jawaharlal Nehru University, New Delhi, India |
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Abstract: | Abstract Amino acid uptake was followed during pH-regulated dimorphism of Candida albicans . It was observed that transport activities of various amino acids differed with the morphological phenotype. The uptake rates of l-alanine , l -phenylalanine and of l -lysine were lower and those of l -methionine were higher in elongated hypha (germ tube), while the rates of glycine, l -glutamic acid and l -proline were similar in bud and hyphal phenotypes. Minimum threshold of amino acids transport activity is required at the time of phenotypic commitment in a diverging population of Candida albicans . |
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Keywords: | Candida albicans Cell divergence Amino acid uptake |
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