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ROS-dependent activation of JNK converts p53 into an efficient inhibitor of oncogenes leading to robust apoptosis |
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| Authors: | Y Shi F Nikulenkov J Zawacka-Pankau H Li R Gabdoulline J Xu S Eriksson E Hedstr?m N Issaeva A Kel E S J Arnér G Selivanova |
| Affiliation: | 1.Department of Microbiology, Tumor and Cell Biology (MTC), Karolinska Institutet, 17177, Stockholm, Sweden;2.Department of Biotechnology, Intercollegiate Faculty of Biotechnology, UG-MUG, 80-822, Gdansk, Poland;3.geneXplain GmbH, D-38302, Wolfenbüttel, Germany;4.Division of Biochemistry, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden |
| Abstract: | |
| Keywords: | TrxR ROS JNK p53 Wip1 inhibition of oncogenes |