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Schizophrenia risk candidate protein ZNF804A interacts with STAT2 and influences interferon-mediated gene transcription in mammalian cells
Affiliation:1. Max‐Delbrück‐Center for Molecular Medicine in the Helmholtz Association (MDC), Laboratory for Neuroproteomics, Berlin, Germany;2. Max‐Delbrück‐Center for Molecular Medicine in the Helmholtz Association (MDC), Laboratory for Mobile DNA, Berlin, Germany;1. Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA;2. Institute for Molecular Virology, University of Minnesota – Twin Cities, Minneapolis, MN 55455, USA;1. German Institute of Human Nutrition (DIfE) Potsdam-Rehbruecke, Germany;2. German Center for Diabetes Research (DZD) Munich Neuherberg, Germany;3. Max-Delbrück Center for Molecular Medicine in the Helmholtz Association Berlin, Germany;4. Institute of Chemistry and Biochemistry, Freie Universität Berlin, Germany;5. Advanced Medical Bioimaging Core Facility – AMBIO, Charité-Universitätsmedizin Berlin, Germany;6. Neuroproteomics, Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC) Berlin, Germany;7. University of Potsdam, Institute of Nutritional Sciences, Nuthetal, Germany;8. Faculty of Health Sciences, Joint Faculty of the Brandenburg University of Technology Cottbus – Senftenberg, the Brandenburg Medical School Theodor Fontane and the University of Potsdam, Germany;1. Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA;2. Department of Chemistry, Grand Valley State University, Allendale, MI 49401, USA;1. Department of Chemistry, Institute of Biochemistry, University of Natural Resources and Life Sciences, Vienna, Austria;2. Department of Biotechnology, Institute of Molecular Biotechnology, University of Natural Resources and Life Sciences, Vienna, Austria;3. St. Anna Children’s Cancer Research Institute, Vienna, Austria;4. Department of Pediatrics, St. Anna Kinderspital, Medical University of Vienna, Vienna, Austria;5. Department of Biotechnology, Institute for Computational Biology, University of Natural Resources and Life Sciences, Vienna, Austria;1. Department of Biological Chemistry, The Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Edmond J. Safra Campus, Givat Ram, Jerusalem 91904, Israel;2. Institute of Chemistry, The Hebrew University of Jerusalem, Edmond J. Safra Campus, Givat Ram, Jerusalem 91904, Israel;3. Department of Biochemistry and Molecular Biology, George S. Wise Faculty of Life Sciences, Tel-Aviv University, Ramat-Aviv, 69978 Tel-Aviv, Israel
Abstract:
Keywords:schizophrenia  ZNF804A protein–protein network  ZNF804A-STAT2 protein complex  signal transduction  interferon response
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