Microenvironment drives cell state,plasticity, and drug response in pancreatic cancer
Institution:
1. Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA;2. Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA;3. Harvard Medical School, Boston, MA 02115, USA;4. Department of Medicine, Brigham and Women’s Hospital, Boston, MA 02115, USA;5. Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA;6. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA;7. Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139, USA;8. Center for Computational Molecular Biology, Brown University, Providence, RI 02912, USA;9. Division of Applied Mathematics, Brown University, Providence, RI 02912, USA;10. Department of Informatics and Analytics, Dana-Farber Cancer Institute, Boston, MA 02215, USA;11. Center for Cancer Genomics, Dana-Farber Cancer Institute, Boston, MA 02215, USA;12. Department of Oncologic Pathology, Dana-Farber Cancer Institute, Boston, MA 02215, USA;13. Massachusetts General Hospital Cancer Center, Boston, MA 02114, USA;14. Department of Surgery, Brigham and Women’s Hospital, Boston, MA 02115, USA;15. Department of Biostatistics, Brown University, Providence, RI 02912, USA;16. Microsoft Research New England, Cambridge, MA 02142, USA;17. Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02142, USA;18. Department of Pathology, Brigham and Women’s Hospital, Boston, MA 02115, USA;19. Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA;1. Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA;2. Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA;3. Harvard Medical School, Boston, MA 02115, USA;4. Department of Medicine, Brigham and Women’s Hospital, Boston, MA 02115, USA;5. Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA;6. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA;7. Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139, USA;8. Center for Computational Molecular Biology, Brown University, Providence, RI 02912, USA;9. Division of Applied Mathematics, Brown University, Providence, RI 02912, USA;10. Department of Informatics and Analytics, Dana-Farber Cancer Institute, Boston, MA 02215, USA;11. Center for Cancer Genomics, Dana-Farber Cancer Institute, Boston, MA 02215, USA;12. Department of Oncologic Pathology, Dana-Farber Cancer Institute, Boston, MA 02215, USA;13. Massachusetts General Hospital Cancer Center, Boston, MA 02114, USA;14. Department of Surgery, Brigham and Women’s Hospital, Boston, MA 02115, USA;15. Department of Biostatistics, Brown University, Providence, RI 02912, USA;16. Microsoft Research New England, Cambridge, MA 02142, USA;17. Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02142, USA;18. Department of Pathology, Brigham and Women’s Hospital, Boston, MA 02115, USA;19. Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA