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Mapping the genetic landscape of DNA double-strand break repair
Institution:1. Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94158, USA;2. Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94158, USA;3. Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA 94158, USA;4. Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA;5. Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08544, USA;6. Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA;7. Editas Medicine, Cambridge, MA 02141, USA;8. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
Abstract:
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  • Keywords:DNA repair  double-strand breaks  functional genomics  genome editing  CRISPR-Cas9
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