Automated mode-of-action detection by metabolic profiling |
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Authors: | Aranìbar N Singh B K Stockton G W Ott K H |
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Affiliation: | BASF Agro Research, Princeton, NJ 08543-0400, USA. |
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Abstract: | Rapid classification and identification of the mode-of-action of bioactive compounds applied to plants can be achieved by a robust and easy-to-use metabolic-profiling method. This method uses artificial neural network analysis of one-dimensional proton NMR spectra of aqueous plant extracts to rapidly classify changes in the total metabolic profile caused by application of crop protection chemicals. |
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