Meclonazepam analogues as potential new antihelmintic agents |
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Authors: | Mahajan Aman Kumar Vipan Mansour Nuha R N Bickle Quentin Chibale Kelly |
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Affiliation: | Department of Chemistry, University of Cape Town, Private Bag, Rondebosh-7701, South Africa. |
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Abstract: | New analogues of the potent antihelmintic meclonazepam were prepared and evaluated against Schistosoma mansoni. The biological data suggests substitution at positions 2 and 4 of meclonazepam could provide promising analogues for prophylactic and therapeutic activity against S. mansoni. |
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