Evidence that AphB, essential for the virulence of Vibrio vulnificus, is a global regulator |
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| Authors: | Jeong Hee Gon Choi Sang Ho |
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| Institution: | Department of Agricultural Biotechnology, Seoul National University, Seoul 151-742, South Korea. |
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| Abstract: | The Vibrio vulnificus aphB mutant was significantly less virulent than the wild type and was impaired in motility and adherence to host cells. Microarray analysis revealed that AphB of V. vulnificus (AphB(Vv)) influences the expression of over 10% of the V. vulnificus genome. The combined results indicated that AphB(Vv) is a global regulator contributing to the pathogenesis of V. vulnificus. |
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