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Assessment of patrilineal gene pool of the Iranian Azeris
Authors:A. Margaryan  Z. Khachatryan  A. Khudoyan  L. Andonian  L. Yepiskoposyan
Affiliation:1. Institute of Molecular Biology, National Academy of Sciences, Yerevan, 0014, Armenia
2. Institute of Man, Yerevan, 0014, Armenia
3. Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, 14155-6446, Iran
Abstract:The Iranian Azeris are the largest ethno-linguistic minority in Iran who live mainly in the north-west part of the country. Located in the crossroad of ancient human migrations the Iranian Azeris bear the complicated historical influence of the region in their gene pool. Despite the importance of Iranian Azeris in reconstructing the historical event of the Middle-East, their (genetic) origin still remains heavily disputed. In this study we tried to evaluate the rates of genetic contribution of possible source populations (namely, indigenous Iranian, Caucasian, and Central Asian) in the gene pool of modem Iranian Azeris through paternally inherited Y-chromosomal 6 STR markers. The assessment of genetic distances reveals that the Iranian Azeris are mixed population with substantial North Caucasian genetic contribution being genetically much closer to their immediate neighboring ethnic groups. Based on the results of admixture analysis we can conclude that there are significant Caucasian and no visible Central Asian contribution to the gene pool of modern Iranian Azeris.
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