Evidence that sister chromatid exchanges and chromatid breaks are two independent events |
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| Authors: | M S Lin W Wertelecki |
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| Institution: | (1) Genetics Division, Los Angeles County-USC Medical Center, University of Southern California, 90033 Los Angeles, California, USA;(2) Department of Medical Genetics, University of South Alabama, 36617 Mobile, Alabama, USA |
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| Abstract: | The relative frequencies of sister chromatid exchanges (SCE) and chromatid breaks in BrdU (5-bromodeoxyuridine) — sensitive site (lq22 lq23) in Chinese hamster cells after BrdU incorporation were studied. The results show that chromatid breaks do not follow the  exchange hypothesis and provide evidence that chromatid breaks and SCEs are two independent events despite some common features. |
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