Minimal electrophoresis time for DNA sequencing. |
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Authors: | A Aldroubi M M Garner |
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Affiliation: | Biomedical Engineering and Instrumentation Program, National Center for Research Resources, National Institutes of Health, Bethesda, MD 20892. |
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Abstract: | This study presents a mathematical approach that allows one to determine the shortest electrophoresis time and migration path length required for DNA sequencing. The calculation was applied to the capillary electrophoresis of a DNA sequencing separation and showed that acceptable resolution could be obtained using a shorter path length than anticipated. |
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