The large first periplasmic loop of SecD and SecF plays an important role in SecDF functioning |
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| Authors: | Nouwen Nico Piwowarek Magdalena Berrelkamp Greetje Driessen Arnold J M |
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| Affiliation: | Department of Microbiology, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Kerklaan 30, 9751 NN Haren, The Netherlands. n.p.nouwen@rug.nl |
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| Abstract: | A remarkable feature of proteins of the SecD and SecF family involved in protein translocation is that they possess a very large first periplasmic domain. Here we report that this large first periplasmic domain is not required for the SecD-SecF interaction but that it is important for catalyzing protein translocation. |
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