An informatic pipeline for the data capture and submission of quantitative proteomic data using iTRAQTM |
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| Authors: | Jennifer A Siepen Neil Swainston Andrew R Jones Sarah R Hart Henning Hermjakob Philip Jones Simon J Hubbard |
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| Affiliation: | (1) Faculty of Life Sciences, University of Manchester, M13 9PT, UK;(2) Manchester Interdisciplinary Biocentre, University of Manchester, UK;(3) School of Computer Science, Faculty of Engineering and Physical Sciences, University of Manchester, UK;(4) MBCMS, School of Chemistry, Manchester Interdisciplinary Biocentre, University of Manchester, UK;(5) EMBL Outstation EBI, Wellcome Trust Genome Campus, Hinxton, Cambs, UK |
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| Abstract: | Background Proteomics continues to play a critical role in post-genomic science as continued advances in mass spectrometry and analytical chemistry support the separation and identification of increasing numbers of peptides and proteins from their characteristic mass spectra. In order to facilitate the sharing of this data, various standard formats have been, and continue to be, developed. Still not fully mature however, these are not yet able to cope with the increasing number of quantitative proteomic technologies that are being developed. |
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