Systematic identification of non-coding RNA 2,2,7-trimethylguanosine cap structures in <Emphasis Type="Italic">Caenorhabditis elegans</Emphasis> |
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| Authors: | Dong Jia Lun Cai Housheng He Geir Skogerbø Tiantian Li Muhammad Nauman Aftab Runsheng Chen |
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| Institution: | (1) Bioinformatics Laboratory, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China;(2) Shanxi Agricultural University, Taigu, Shanxi, 030801, China;(3) Bioinformatics Research Group, Key Laboratory of Intelligent Information Processing, Institute of Computing Technology, Chinese Academy of Sciences, Beijing, 100080, China;(4) Graduate School of the Chinese Academy of Sciences, Beijing, 100039, China |
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| Abstract: | Background The 2,2,7-trimethylguanosine (TMG) cap structure is an important functional characteristic of ncRNAs with critical cellular
roles, such as some snRNAs. Here we used immunoprecipitation with both K121 and R1131 anti-TMG antibodies to systematically
identify the TMG cap structures for all presently characterized ncRNAs in C. elegans. |
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