| 宏基因组学在新型生物催化剂开发中的研究进展 |
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| 引用本文： | 钱莉莉,陈少欣,史炳照. 宏基因组学在新型生物催化剂开发中的研究进展[J]. 微生物学杂志, 2006, 26(4): 68-71 |
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| 作者姓名： | 钱莉莉 陈少欣 史炳照 |
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| 作者单位： | 上海医药工业研究院,上海,200040 |
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| 摘 要： | 宏基因组学是基因工程发展的新方向,它为寻找和发现新的功能基因及生物催化剂提供了新的研究策略。着重论述了宏基因组学的研究方法,包括DNA的提取、文库的构建以及筛选策略的选择。同时介绍了近年来宏基因组学应用于新型生物催化剂开发中所取得的一些成果。
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| 关 键 词： | 宏基因组学 不可培养微生物 生物催化剂 筛选 |
| 文章编号： | 1005-7021(2006)04-0068-04 |
| 修稿时间： | 2005-08-31 |
Advance in Metagenomics on the Development of New Biocatalyst |
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| QIAN Li-li,CHEN Shao-xin,SHI Bing-zhao. Advance in Metagenomics on the Development of New Biocatalyst[J]. Journal of Microbiology, 2006, 26(4): 68-71 |
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| Authors: | QIAN Li-li CHEN Shao-xin SHI Bing-zhao |
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| Affiliation: | Shanghai Inst.of Pharm.Indust.Shanghai 200040 |
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| Abstract: | Metagenomics is a new orientation of the development of genetic engineering.It provides a new strategy for seeking novel functional gene and biocatalyst.Methods in metagenomic study,including DNA extraction,library construction and screening were discussed in this paper.Meanwhile,the achievements of the application of metagenomics in the development of biocatalyst were also introduced. |
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| Keywords: | metagenomics uncultured microorganisms biocatalyst screening |
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