Nomenclature and listing of celiac disease relevant gluten T-cell epitopes restricted by HLA-DQ molecules |
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| Authors: | Ludvig M. Sollid Shuo-Wang Qiao Robert P. Anderson Carmen Gianfrani Frits Koning |
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| Affiliation: | Centre for Immune Regulation and Department of Immunology, University of Oslo and Oslo University Hospital, Rikshospitalet, Oslo, Norway. l.m.sollid@medisin.uio.no |
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| Abstract: | Celiac disease is caused by an abnormal intestinal T-cell response to gluten proteins of wheat, barley and rye. Over the last few years, a number of gluten T-cell epitopes restricted by celiac disease associated HLA-DQ molecules have been characterized. In this work, we give an overview of these epitopes and suggest a comprehensive, new nomenclature. |
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