The replication of Escherichia coli chromosome can be initiated by integrated ColE1-type plasmids |
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| Authors: | N I Strizhov L P Tikhomirova and A A Bayev |
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| Institution: | (1) Institute of Biochemistry and Physiology of Microorganisms, USSR Academy of Sciences, 142292 Pushchino, Moscow region, USSR |
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| Abstract: | Summary When integrated in the chromosome of E. coli by site-specific recombination of  , the ColE1 type replicator provokes the phenotypic suppression of CRT46 dnaA strain. The level of this suppression depends on the orientation of ColE1 replicator in the chromosome of bacteria. Integrative plasmids (intmids) coexist in both autonomous and extrachromosomal states in the same cell. |
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