Uptake and acylation of 2-acyl-lysophospholipids by Escherichia coli. |
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| Authors: | L Hsu S Jackowski C O Rock |
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| Affiliation: | Department of Biochemistry, St. Jude Children's Research Hospital, Memphis, Tennessee 38101. |
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| Abstract: | The efficiency of extracellular 2-acyl-lysophospholipid incorporation into Escherichia coli membranes and the acyl donor utilized to acylate the 2-acyl-lysophospholipid was determined. Exogenous 2-acyl-lysophospholipids were acylated via the acyl-acyl carrier protein synthetase/2-acylglycerophosphoethanolamine acyltransferase pathway. The maximum extent of 2-acyl-lysophospholipid incorporation into the membrane was approximately 2.5% of the normal phospholipid biosynthetic rate. |
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