Interphase chromosome-specific multicolor banding (ICS-MCB): a new tool for analysis of interphase chromosomes in their integrity |
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| Authors: | Iourov Ivan Y Liehr Thomas Vorsanova Svetlana G Yurov Yuri B |
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| Institution: | National Research Center of Mental Health, RAMS, Moscow, Russia. ivan_iourov@yahoo.com |
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| Abstract: | Biomedical research of interphase chromosomes in their integrity is hindered by technical limitations. We introduce a technology using microdissection-based engineering of DNA probes and fluorescence multicolor chromosome banding that allows studying interphase chromosome organization, numbers and rearrangements in somatic cells. |
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