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Structure-based optimization of FDA-approved drug methylene blue as a c-myc G-quadruplex DNA stabilizer
Authors:Chan Daniel Shiu-Hin  Yang Hui  Kwan Maria Hiu-Tung  Cheng Zhen  Lee Paul  Bai Li-Ping  Jiang Zhi-Hong  Wong Chun-Yuen  Fong Wang-Fun  Leung Chung-Hang  Ma Dik-Lung
Affiliation:a Department of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China
b Centre for Cancer and Inflammation Research, School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China
c Department of Biology and Chemistry, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong, China
Abstract:
Keywords:c-myc G-quadruplex   Methylene blue   FDA-approved drug   Repurposing   Structure-based optimization
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