Complex links between dietary lipids, endogenous endotoxins and metabolic inflammation |
| |
Authors: | Fabienne Laugerette Cécile Vors Noël Peretti Marie-Caroline Michalski |
| |
Institution: | a Universite de Lyon, F-69100 Villeurbanne, France b INSERM, U870, RMND, F-69621 Villeurbanne, France c INSA-Lyon, IMBL, F-69621 Villeurbanne, France d INRA, UMR 1235, RMND, F-69921 Oullins, France e CRNH Rhône-Alpes, F-69921 Oullins, France f Hospices Civils de Lyon, Hopitâl Femme Mère Enfant, F-69500 Bron, France |
| |
Abstract: | Metabolic diseases such as obesity are characterized by a subclinical inflammatory state that contributes to the development of insulin resistance and atherosclerosis. Recent reports also indicate that (i) there are alterations of the intestinal microbiota in metabolic diseases and (ii) absorption of endogenous endotoxins (namely lipopolysaccharides, LPS) can occur, particularly during the digestion of lipids. The aim of the present review is to highlight recently gained knowledge regarding the links between high fat diets, lipid digestion, intestinal microbiota and metabolic endotoxemia & inflammation. |
| |
Keywords: | Nutrition Obesity Lipid Inflammation Endotoxemia |
本文献已被 ScienceDirect 等数据库收录! |
|