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DNA methylation and the frequency of CpG in animal DNA. |
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| Authors: | A P Bird |
| Abstract: | An analysis of nearest neighbour dinucleotide frequencies and the level of DNA methylation in animals strongly supports the suggestion that 5-methylcytosine (5mC) tends to mutate abnormally frequently to T. This tendency is the likely cause of the CpG deficiency in heavily methylated genomes. |
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