catmap: Case-control And TDT Meta-Analysis Package |
| |
| Authors: | Kristin K Nicodemus |
| |
| Institution: | (1) Genes, Cognition and Psychosis Program, Clinical Brain Disorders Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USA;(2) Current address: Wellcome Trust Centre for Human Genetics, Roosevelt Drive, Oxford, OX3 7BN, UK;(3) Department of Clinical Pharmacology, University of Oxford, Radcliffe Infirmary, Woodstock Road, Oxford, OX2 6HA, UK |
| |
| Abstract: | Background Risk for complex disease is thought to be controlled by multiple genetic risk factors, each with small individual effects.
Meta-analyses of several independent studies may be helpful to increase the ability to detect association when effect sizes
are modest. Although many software options are available for meta-analysis of genetic case-control data, no currently available
software implements the method described by Kazeem and Farrall (2005), which combines data from independent family-based and
case-control studies. |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
|
