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Optimization for two-step biochemical kinetic resolution of enantiomers
Authors:Shengdong Zhu   Yuanxin Wu  Ziniu Yu
Affiliation: a School of Chemical Engineering and Pharmacy, Wuhan Institute of Chemical Technology, Hubei Key Laboratory of Novel Chemical Reactor and Green Chemical Technology, Wuhan, P.R. Chinab College of Life Science and Technology, Huazhong Agricultural University, Wuhan, P.R. China
Abstract:A method is presented to optimize the two-step biochemical kinetic resolution of enantiomers. The optimization results were verified experimentally via the enantioselective hydrolysis of ketoprofen methyl ester and the enantioselective esterification of ketoprofen.
Keywords:Biochemical kinetic resolution  ketoprofen  optimization
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