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Categorization of humans in biomedical research: genes,race and disease
Authors:Email author" target="_blank">Neil?RischEmail author  Esteban?Burchard  Elad?Ziv  Hua?Tang
Institution:(1) Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305-5120, USA;(2) Division of Research, Kaiser Permanente, Oakland, CA 94611-5714, USA;(3) Department of Medicine, University of California, San Francisco, CA 94143, USA;(4) Department of Statistics, Stanford University, Stanford, CA 94305, USA
Abstract:A debate has arisen regarding the validity of racial/ethnic categories for biomedical and genetic research. Some claim 'no biological basis for race' while others advocate a 'race-neutral' approach, using genetic clustering rather than self-identified ethnicity for human genetic categorization. We provide an epidemiologic perspective on the issue of human categorization in biomedical and genetic research that strongly supports the continued use of self-identified race and ethnicity.
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