SUPFAM: A database of sequence superfamilies of protein domains |
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| Authors: | Shashi B Pandit Rana Bhadra VS Gowri S Balaji B Anand N Srinivasan |
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| Affiliation: | (1) Molecular Biophysics Unit, Indian Institute of Science, Bangalore, 560 012, India;(2) National Centre for Biological Sciences, Tata Institute of Fundamental Research, UAS-GKVK campus, Bangalore, 560 065, India;(3) Department of Biosciences and Bioengineering, Indian Institute of Technology, Kanpur, Kanpur, 208 016, India |
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| Abstract: | Background SUPFAM database is a compilation of superfamily relationships between protein domain families of either known or unknown 3-D structure. In SUPFAM, sequence families from Pfam and structural families from SCOP are associated, using profile matching, to result in sequence superfamilies of known structure. Subsequently all-against-all family profile matches are made to deduce a list of new potential superfamilies of yet unknown structure. |
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