Short- and middle-latency auditory evoked potentials in abstinent chronic alcoholics: preliminary findings |
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Affiliation: | 1. Center for Health Sciences, SRI International, Menlo Park, CA, USA;2. Melbourne School of Psychological Sciences, The University of Melbourne, Parkville, Vic., Australia;3. Brain Function Research Group, School of Physiology, University of the Witwatersrand, Johannesburg, South Africa |
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Abstract: | Short- and middle-latency auditory evoked potentials (BAEPs and MAEPs) were studied in 15 chronic alcoholic patients after 1 month's abstinence and compared with those of 15 healthy controls, matching the patients pairwise for sex and age. Most of the parameters studied varied more within the alcoholic group than within the control group. The BAEP results agree with previous reports; in the alcoholic group, BAEP peak V was significantly delayed and the inter-peak intervals, III–V and I–V, were lengthened. The latencies of the MAEP components Na and Pa, on the other hand, were significantly shortened. These findings suggest that chronic abusive consumption of alcohol may bring about structural and/or neurochemical alterations at various levels in the auditory pathway. |
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