Human middle-latency auditory evoked potentials: vertex and temporal components |
| |
| Institution: | 1. Department of Surgery, Albany Medical College, Albany, NY 12208 U.S.A.;2. Department of Neurology, Albany Medical College, Albany, NY 12208 U.S.A.;3. Department of Anatomy, Albany Medical College, Albany, NY 12208 U.S.A.;4. Wadsworth Center for Laboratories and Research, New York State Department of Health, Albany, NY 12201 U.S.A.;1. Division of Communication and Auditory Neuroscience, House Research Institute, Los Angeles, CA, USA;2. Department of Head and Neck Surgery, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA;3. Department of Otorhinolaryngology, Head and Neck Surgery, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands;4. Research School of Behavioral and Cognitive Neurosciences, Graduate School of Medical Sciences, University of Groningen, Groningen, The Netherlands;1. Division of Pediatric Otolaryngology, Medical College of Wisconsin, 9000 W Wisconsin Avenue, Milwaukee, WI 53226, USA;2. Department of Otolaryngology and Communication Sciences, Medical College of Wisconsin, 9000 W Wisconsin Avenue, Milwaukee, WI 53226, USA;3. Institute for Health and Society, Medical College of Wisconsin, 9000 W Wisconsin Avenue, Milwaukee, WI 53226, USA;1. Department of Otology and Laryngology, Harvard Medical School, Boston MA, USA;2. Eaton-Peabody Laboratory, Massachusetts Eye & Ear Infirmary, Boston MA, USA;3. Harvard Program in Speech and Hearing Bioscience and Technology, Boston MA, USA;1. Washington University School of Medicine in St. Louis, Department of Otolaryngology, Saint Louis, MO, USA;2. University of Iowa, Department of Communication Sciences and Disorders, Iowa City, IA, USA;1. Discipline of Speech Science, School of Psychology, University of Auckland, Auckland, New Zealand;2. Section of Audiology, University of Auckland, Auckland, New Zealand;3. Eriksholm Research Centre, Denmark |
| |
| Abstract: | We recorded middle-latency (20–70 msec) auditory evoked potentials (MLAEPs) to monaural and binaural clicks in 30 normal adults (ages 20–49 years) at 32 scalp locations all referred to a balanced non-cephalic reference. Our goal was to define the MLAEP components that were present at comparable latencies and comparable locations across the subject population. Group and individual data were evaluated both as topographic maps and as MLAEPs at selected electrode locations.Three major components occurred between 20 and 70 msec, two well-known peaks centered at the vertex, and one previously undefined peak focused over the posterior temporal area. Pa is a 29 msec positive peak centered at the vertex and present with both monaural and binaural stimulation, Pb is a 53 msec positive peak also centered at the vertex but seen consistently only with binaural and right ear stimulation. TP41 is a 41 msec positive peak focused over both temporal areas. TP41 has not been identified in previous MLAEP studies that concentrated on central scalp locations and/or used active reference electrode sites such as ears or mastoids.Available topographic, intracranial, pharmacologic, and lesion studies indicate that Pa, Pb and TP41 are of neural origin. Whether Pa and/or Pb are produced in Heschl's gyrus, primary auditory cortex, remains unclear. TP41 is probably produced by auditory cortex on the posterior lateral surface of the temporal lobe. It should prove of considerable value in experimental and clinical evaluation of higher level auditory function in particular and of cortical function in general. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
