Biotransformation of 2,2-Dimethyl-1,3-Propanediol to 3-Hydroxypivalic Acid by Acetobacter Acetii DSMZ3508 and Related Bacteria |
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| Authors: | Bernd Füchtenbusch Marc Wältermann Alexander Steinbüchel |
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| Affiliation: | (1) Institut für Mikrobiologe der Westfälischen Wilhelms-Universität Münster, Corrensstraße 3, D-48149 Münster, Germany |
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| Abstract: | Acetobacter acetii DSMZ3508 and related bacteria converted 2,2-dimethyl-1,3-propanediol into 3-hydroxypivalic acid (2,2-dimethyl-3-hydroxypropionic acid; 3HP) during submerged cultivation in mineral salt medium. The maximum yield of 3-hydroxypivalic acid was 24.4% of the fed substrate after 18 days. Cultivation parameters, as pH, cell density, optimal substrate concentration, and oxygen supply for the bioconversion process were determined. |
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