Replication forks, chromatin loops and dormant replication origins |
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| Authors: | J Julian Blow and Xin Quan Ge |
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| Affiliation: | (1) Wellcome Trust Centre for Gene Regulation and Expression, College of Life Sciences, University of Dundee, Dow Street, Dundee, DD1 5EH, UK |
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| Abstract: | When DNA replication is slowed down, normally dormant replication origins are activated. Recent work demonstrates that cells adapt by changing the organization of chromatin loops and maintaining the new pattern of origin use in subsequent cell cycles. |
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