| Abstract: | A histomorphological investigation of the corpus luteum has been performed in 60 women with an unchanged menstrual cycle. Physiological changes of the corpus luteum are reliably reflected in the karyometry results, in correlation between immature, mature and distrophic luteocytes, their mitotic activity and in total thickness of the parenchymatous layer. The parameters taken into account are united into a total index of the corpus luteum activity, its functional significance is proved when a parallel estimation of microelements content (zinc and copper) is performed in the corpus luteum tissues. The morphometric indices used demonstrate that the menstrual corpus luteum is mainly formed at the expense of a combined hypertrophy of granulous and theca-lutein cells and maturation of the preceding cellular forms. Regressive changes are characterized by a decreasing volume of the nuclei and distrophic changes of luteocytes, which are especially manifested at the end of the menstrual cycle. |
