Derivatives of L-adenosine and L-guanosine as substrates for human deoxycytidine kinase. |
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Authors: | G Gaubert G Gosselin J L Imbach S Eriksson G Maury |
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Affiliation: | Laboratoire de Chimie Bioorganique, UMR 5625 du CNRS, Université Montpellier II, France. |
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Abstract: | A series of analogues of L-adenosine and of L-guanosine, including beta-L-dA, beta-L-Ado, beta-L-araA, and beta-L-dG, have been shown to be substrates of human deoxycytidine kinase thus demonstrating the complete lack of enantioselectivity of this enzyme. |
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